Enhancement of Solubility and Dissolution Rate of Carvedilol by Using Fluidized-bed Granulation Technique
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چکیده
منابع مشابه
Enhancement of solubility and dissolution rate of Fenofibrate by melt granulation technique
This work describes a melt granulation technique to improve the solubility and dissolution characteristics of a poorly water-soluble drug Fenofibrate (FNO). Melt granulation technique is a process by which pharmaceutical powders are efficiently agglomerated by a meltable polymers and surfactants. The advantage of this technique compared to a conventional granulation is that no water or organic ...
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Here, we statistically identified the critical factor of the granulation rate during the fluidized bed granulation process. Lactose was selected as the excipient and was granulated with several binders, including hydroxypropyl cellulose, hydroxypropyl methyl cellulose, and polyvinylpyrrolidone. The viscosity, density, and surface tension of the binder solution, contact angle, and the work done ...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences Review and Research
سال: 2020
ISSN: 0976-044X
DOI: 10.47583/ijpsrr.2020.v65i01.027